Mounjaro
Most commercial insurance plans cover Mounjaro for Type 2 diabetes. Medicare Part D may also cover it, but usually requires trying other diabetes medications first.
Zepbound
Insurance coverage for weight loss medications is limited. Many plans don’t cover them at all, which means you may have to pay full price if using Tirzepatide for weight loss instead of diabetes.
Tirzepatide Cost Without Insurance
Uninsured patients face the full retail pricing burden, creating significant affordability challenges. Without insurance or manufacturer discounts, the medication can cost $19,200 per year.
| Medication |
Monthly Cost |
Quarterly Cost |
Annual Cost |
| Mounjaro |
$1,300-$1,600 |
$3,900 – $4,800 |
$15,600-$19,200 |
| Zepbound |
$1,060-$1,200 |
$3,180 – $3,600 |
$12,720-$14,400 |
| Personalized GLP-1 Injections |
From $197 |
From $591 |
From $2364 |
Mounjaro
Without insurance, maintaining Mounjaro medication requires significant financial planning. Many patients explore switching from semaglutide to tirzepatide to access better efficacy despite higher costs.
The medication's proven diabetes management benefits often justify the expense for patients with adequate financial resources.
Zepbound
Because Zepbound is explicitly approved for weight loss, uninsured patients may face steeper costs and fewer savings programs than those using diabetes medications.
This often leads people to compare Semaglutide vs Tirzepatide to find a more cost-effective, yet equally effective, alternative.
Ways to Save on Tirzepatide Cost
Multiple proven strategies can reduce Tirzepatide costs by 50-90%, making treatment accessible for more patients.
Manufacturer Coupons and Savings Programs
Eli Lilly offers comprehensive savings programs for both Mounjaro and Zepbound. You will automatically receive the $499 purchase offer on your first purchase of the 7.5 mg and 10 mg Zepbound vial.
The Mounjaro Savings Card reduces monthly costs to $25 for eligible commercial insurance patients. Zepbound offers similar programs with monthly caps of around $25-$150, depending on insurance status.
Compounded Tirzepatide Through Telehealth
Compounded Tirzepatide provides FDA-regulated alternatives at substantially reduced costs. Licensed compounding pharmacies create personalized formulations under healthcare provider supervision.
Telehealth providers like IVY RX offer personalized GLP-1 injections at 60-80% cost savings compared to brand medications.
Patient Assistance Programs
Eli Lilly's patient assistance programs provide free medications for qualifying low-income patients. Income requirements typically fall below 300% of the federal poverty guidelines.
Application processes require detailed financial documentation and healthcare provider coordination, but successful applicants receive 12-month medication supplies at no cost.
Pharmacy Shopping and Cash Discounts
Different pharmacies offer varying cash prices, with potential savings of $100-$300 monthly. Online pharmacies, warehouse clubs, and independent pharmacies often provide competitive pricing.
GoodRx and similar platforms offer additional discount opportunities, though savings remain limited given tirzepatide's premium pricing structure.
Consider personalized GLP-1 injections as a cost-effective alternative that maintains therapeutic benefits while dramatically reducing monthly expenses.
Cheaper Tirzepatide Alternatives (Cost Comparison)
Several medications offer similar weight loss and metabolic benefits at lower costs than Tirzepatide.
Understanding these alternatives helps you make informed treatment decisions based on both efficacy and affordability.
| Treatment Option |
Average Weight Loss |
Monthly Cost (Without Insurance) |
Monthly Cost (With Insurance) |
Administration |
| Personalized GLP-1 (IVY RX) |
10-18% |
From $197 |
Not required |
Weekly injection |
| Ozempic |
10-14% |
$900–$1,000 |
$25-$200 |
Weekly injection |
| Wegovy |
12-15% |
$1,200–$1,400 |
$25-$500 |
Weekly injection |
| Liraglutide (Saxenda) |
5-8% |
$1,300-$1,500 |
$25-$400 |
Daily injection |
| Semaglutide Tablets (Rybelsus) |
3-5% |
$900–$1,000 |
$25-$200 |
Daily oral |
| Compounded Semaglutide |
8-12% |
$200–$450 |
Not required |
Weekly injection |
Personalized GLP-1 Injections (IVY RX)
IVY RX's personalized approach combines the therapeutic benefits of GLP-1 medications with significant cost savings.
These compounded formulations use the same active ingredients as brand medications but at 70-80% lower costs.
The telehealth model eliminates insurance complications while providing comprehensive medical support, making treatment accessible regardless of coverage status.
Access personalized GLP-1 injection treatments with Ivy.
Semaglutide (Ozempic/Wegovy)
Semaglutide offers proven weight loss results with slightly better insurance coverage than Tirzepatide.
Many patients explore semaglutide vs Mounjaro comparisons before choosing their optimal treatment path.
The medication's longer market presence has created more cost-reduction opportunities and insurance familiarity.
Liraglutide (Saxenda)
While less effective than newer GLP-1 medications, liraglutide offers an established safety profile with reasonable insurance coverage for weight management.
Liraglutide vs semaglutide comparisons help patients understand trade-offs between cost, efficacy, and convenience.
Oral semaglutide (Rybelsus)
Semaglutide tablets provide convenience for injection-averse patients, though with reduced efficacy compared to injectable formulations.
The oral option often costs 20-30% less than injections while maintaining some therapeutic benefits.
Consider Semaglutide pills vs injection differences when evaluating treatment options based on your preferences and budget constraints.
Compounded Semaglutide
Compounded semaglutide delivers the same active ingredient as brand-name options, at a fraction of the price.
It’s a cost-effective alternative for those without insurance or facing high retail costs — typically priced between $200–$450 per month through telehealth providers.
Many users switch from Mounjaro or Wegovy to compounded semaglutide for continued results without the financial strain.
Get Started on Your Weight Loss Journey With IVY RX
Tirzepatide delivers real results, but for many, the price tag makes it unsustainable. Fortunately, you don’t have to choose between effectiveness and affordability.
IvyRx offers personalized GLP-1 injection treatments using the same active ingredients as leading medications, at a fraction of the cost.
With telehealth support, customized dosing, and no insurance hoops to jump through, it’s a more innovative way to get started.
Start your 5-minute assessment with IVY RX today — and get your treatment delivered in as little as 2 days.
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