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GLP-1 Boost: Important Safety Information
1. Introduction
- What is GLP-1 Boost?
GLP-1 Boost is a dietary supplement designed to support healthy metabolism, inspired by mechanisms of glucagon-like peptide-1 (GLP-1). It is formulated with a proprietary blend of hops extract, beetroot powder, nicotinamide mononucleotide (NMN), and berberine, encapsulated in a vegetable capsule (HPMC). - Why GLP-1?
GLP-1 is a hormone known for its glucose-dependent insulin secretion, regulation of gastric emptying, and appetite modulation. It is also studied for its possible anti-inflammatory, cardio- and neuroprotective effects, as well as reduced apoptosis and potential support for learning and memory. - Regulatory Status
GLP-1 Boost is not an FDA-approved product. If you require an FDA-approved medication, such as prescription GLP-1 receptor agonists (e.g., semaglutide, tirzepatide), please consult your healthcare provider for alternatives.
2. Potential Benefits & Ingredients
- Hops Extract
- Known for its antioxidant (polyphenols), anti-inflammatory, and antimicrobial properties.
- May have positive impacts on digestion and relaxation/sleep.
-
- Beetroot Powder
- Rich in betalains (betanin) and nitrates, which can help support antioxidant pathways and potentially reduce LDL cholesterol.
- May contribute to improved exercise capacity and reduced muscle soreness.
-
- Nicotinamide Mononucleotide (NMN)
- A precursor to NAD+, essential for cellular energy and repair processes.
- Often discussed in the context of healthy aging, cellular metabolism, and pro-survival mechanisms.
-
- Berberine
- A plant alkaloid widely used in Eastern medicine for digestive disorders and skin conditions.
- Studies suggest it may help regulate glucose and lipid metabolism and may have hypoglycemic (blood sugar–lowering) properties.
Note on Research
- While some in vitro and animal studies (and small human trials for berberine) show promise for these individual ingredients, robust clinical data in humans on this exact combination (GLP-1 Boost) is currently limited.
- The blend is formulated to mimic or support processes linked to GLP-1 receptor agonists; however, it is not a substitute for prescribed medications.
3. Who Should Avoid or Use Caution
You should not take GLP-1 Boost if you:
- Are pregnant, trying to become pregnant, or breastfeeding, unless specifically advised by a qualified healthcare professional.
- Have a known allergy or hypersensitivity to any of the listed ingredients (hops, beetroot, NMN, berberine) or the capsule constituents.
- Have severe or unstable medical conditions (e.g., advanced liver disease, kidney disease, or heart failure) without close medical supervision.
Consult your healthcare provider before starting GLP-1 Boost if you:
- Have type 1 diabetes, uncontrolled type 2 diabetes, or require insulin therapy.
- Are on medications for blood sugar control (e.g., sulfonylureas, metformin) or other supplements that may interact with these ingredients.
- Have a history of severe gastrointestinal disorders or any condition affecting nutrient absorption.
- Have underlying conditions involving blood pressure, as beetroot nitrates may influence nitric oxide pathways.
4. Possible Side Effects
Although many individuals may tolerate GLP-1 Boost without incident, you could experience:
- Gastrointestinal Distress
- Mild bloating, gas, or changes in bowel habits.
- If persistent or severe, consult a healthcare professional.
-
- Allergic Reactions
- Itching, hives, swelling of the lips/tongue/face, or difficulty breathing (possible anaphylaxis).
- Discontinue immediately and seek medical attention if you suspect an allergic reaction.
-
- Headache or Dizziness
- May occur if you are sensitive to changes in blood sugar or blood pressure.
- If pronounced, discontinue and consult a qualified provider.
-
- Blood Sugar Fluctuations
- Possible for those who are on other hypoglycemic agents or have impaired glucose tolerance.
- Monitor blood sugar levels as advised by your physician.
-
- Low Blood Pressure
- Especially if combined with other blood pressure–lowering agents or if you are prone to hypotension.
5. Drug Interactions
- Medications for Diabetes
- Berberine and NMN may influence glucose metabolism and insulin sensitivity; combining them with anti-diabetic medications may increase the risk of hypoglycemia.
- Blood Pressure Medications
- Beetroot (and its nitric oxide effects) could influence blood pressure, requiring careful monitoring with antihypertensives.
- Other Supplements or Herbs
- Hops or berberine might potentiate or reduce the efficacy of other herbal therapies or supplements.
- Always Inform Your Healthcare Provider
- Disclose all prescription drugs, over-the-counter medications, vitamins, and herbal products you are taking before starting GLP-1 Boost.
6. Usage & Dosing
- Recommended Dosage
- Follow instructions provided on the label or as directed by your healthcare professional.
- Do not exceed the recommended serving size without professional guidance.
- Timing
- Some components may be better absorbed with meals. Check with a healthcare professional for best timing.
- Storage
- Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
7. Additional Considerations
- Not a Substitute for Prescription Medications
- GLP-1 Boost is a dietary supplement, not a prescription GLP-1 receptor agonist (e.g., semaglutide, tirzepatide). It should not replace medications prescribed for metabolic disorders or diabetes.
- Lifestyle Factors
- For optimal results, combine this supplement with a balanced diet, regular exercise, proper hydration, and adequate rest.
- Individual Results May Vary
- Response to dietary supplements can differ significantly among individuals based on genetics, health status, and lifestyle factors.
8. Disclaimer
- Not Evaluated by the FDA
- These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- Consult a Professional
- This information is provided for educational purposes only and does not replace professional medical advice.
- No Guaranteed Outcomes
- While some evidence supports the individual ingredients, results are not guaranteed, and research is still evolving.
9. Reporting Adverse Events
- Seek Medical Care
- If you experience severe side effects or adverse events (e.g., difficulty breathing, severe allergic reactions, acute hypoglycemia), discontinue use and seek immediate medical attention.
- FDA MedWatch
- You or your healthcare provider can report suspected adverse reactions to the FDA’s MedWatch Program by calling 1-800-FDA-1088 or visiting www.fda.gov/medwatch.
Questions or Concerns?
If you have any questions regarding GLP-1 Boost—whether about potential benefits, side effects, or interactions—please consult a qualified healthcare professional.
BPC-157: Important Safety Information
1. Introduction
- What is BPC-157?
BPC-157 is a synthetic peptide derived from a fifteen-amino-acid sequence found in human gastric juice. It is theorized to promote angiogenesis (the development of new blood vessels), which may support increased blood flow and nutrient transport to tissues. - Mechanism of Action
Research suggests that BPC-157 regulates Vaso Endothelial Growth Factor (VEGF) and plays a role in promoting healing, offering cytoprotective properties, and potentially influencing the gut-brain axis and microbiota balance. - Regulatory Status
BPC-157 is not approved by the U.S. Food and Drug Administration (FDA) for any specific medical indication. If you require an FDA-approved therapy, please speak with your healthcare provider about alternative options.
2. Potential Uses & Research
- Regenerative Properties
Emerging literature (primarily from animal models) indicates BPC-157 may help support tissue regeneration, particularly in tendons, ligaments, and skeletal muscle recovery. - Gut-Brain Axis Support
Studies explore BPC-157’s potential role in regulating gut microbiota, influencing cognitive and emotional functioning via the gut-brain axis, and supporting the autonomic, hypothalamic-pituitary-adrenal (HPA), and gastrointestinal (GI) nerve connections. - Inflammation & CNS Disorders
Preliminary data suggest BPC-157 may reduce inflammation, support nerve recovery, and improve outcomes in central nervous system (CNS) disorders. - Limited Human Trials
While animal and preliminary in vitro research is promising, there are few well-controlled human clinical trials on BPC-157, and more data is needed to confirm safety, efficacy, and dosing parameters.
3. Contraindications & Precautions
You should not use BPC-157 if you:
- Are pregnant, planning to become pregnant, or breastfeeding without specific medical advice, as safety data in these populations are lacking.
- Have a known allergy or hypersensitivity to BPC-157 or any ingredient used in its formulation.
- Suffer from severe or unstable medical conditions (e.g., uncontrolled diabetes, advanced kidney/liver disease) without consulting a qualified healthcare professional.
Please consult your healthcare provider before using BPC-157 if you have:
- A history of autoimmune or chronic inflammatory disorders.
- Active malignancies or are undergoing cancer treatment.
- Any serious health conditions requiring ongoing medical management.
4. Possible Side Effects
Although formal human safety data is limited, potential side effects from anecdotal reports or small-scale studies include:
- Injection Site Reactions (if administered via injection)
- Redness, swelling, pain, or irritation at the site of injection.
- Seek medical attention if signs of infection (e.g., warmth, pus) develop.
-
- Gastrointestinal Upset
- Nausea, changes in bowel habits, or mild cramping.
- If GI symptoms are severe or persistent, consult a healthcare professional.
-
- Allergic Reactions
- Rash, itching, swelling of the face/lips/tongue, or difficulty breathing (possible anaphylaxis).
- Discontinue use and seek emergency care if you suspect a severe allergic reaction.
-
- Changes in Mood or Energy
- Some users report shifts in mood, energy levels, or sleep patterns.
- If significant, discuss with your healthcare provider.
Because of limited large-scale studies, other potential side effects may not yet be identified. Always report any unusual symptoms to a medical professional.
5. Administration & Dosage
- Route & Formulation
- BPC-157 may be compounded in various forms, including capsules, subcutaneous injections, or topical formulations.
- The appropriate route depends on the specific condition and medical guidance.
-
- Dosage
- There is no standardized dosing protocol for BPC-157 in humans.
- Your healthcare provider may recommend a customized regimen based on factors such as body weight, medical history, and treatment goals.
-
- Monitoring
- Regular follow-up appointments may be advised to assess tolerance, response, or any side effects.
- Notify your practitioner of any changes in health status during use.
6. Warnings & Limitations
- Off-Label and Experimental Use
BPC-157 is not FDA-approved for any indication; therefore, its use should be considered experimental or off-label. - Limited Human Data
Much of the evidence supporting BPC-157’s benefits comes from animal or in vitro models. Caution is advised until more robust human data is available. - Not a Substitute for Standard Medical Care
BPC-157 should not replace conventional therapies prescribed for medical conditions such as inflammatory diseases, tendon injuries, or gastrointestinal disorders. - Risk vs. Benefit
Discuss potential benefits and risks with your qualified healthcare provider before initiating therapy.
7. Drug Interactions
- Concomitant Medications
- Inform your healthcare provider about any prescription medications, over-the-counter drugs, supplements, or herbal products you are taking.
- Interactions or additive effects on inflammation, tissue repair, or vascular health remain poorly characterized.
8. Storage & Handling
- Temperature & Light
- Store in a cool, dry place, typically refrigerated if instructed by your compounder or pharmacist.
- Protect from direct sunlight and moisture.
- Expiration
- Do not use BPC-157 beyond its expiration date or if the product shows signs of contamination or degradation.
9. Reporting Adverse Events
- Seek Immediate Medical Attention
- If you experience severe adverse events such as difficulty breathing, chest pain, significant swelling, or sudden confusion, seek emergency care.
- Adverse Event Reporting
- Contact your healthcare professional to report any unexpected reactions.
- You can also file a report with the FDA’s MedWatch Program at 1-800-FDA-1088 or online at www.fda.gov/medwatch.
10. Disclaimer
- Not Evaluated by the FDA
- BPC-157 has not been approved by the FDA to diagnose, treat, cure, or prevent any disease.
- Informational Purposes Only
- This document provides general educational information and should not replace advice from a licensed medical professional.
- Individual Variation
- Response to BPC-157 may vary significantly; no outcomes are guaranteed.
Questions or Concerns?
If you have any questions regarding BPC-157, including its mechanism of action, safety profile, or potential off-label uses, please consult a qualified healthcare professional.
Gut Peptide Complex: Important Safety Information
- Introduction
What is Gut Peptide Complex?
Gut Peptide Complex is a comprehensive probiotic-plus supplement capsule designed to support a balanced gut microbiota and healthy gut-brain axis function. Its formula includes multiple active ingredients, such as KPV, BPC, GHK-Cu, Larazotide, Laxogenin, and a proprietary 11-strain probiotic blend. This synergistic combination may help modulate inflammatory responses, promote soft tissue healing, and support nerve recovery and metabolic balance.
Mechanism of Action- Targets the gut-brain axis with multiple bioactive compounds that may support healthy inflammatory responses and microbial balance.
- Includes peptides (e.g., KPV, BPC) potentially involved in tissue healing, nerve repair, and improved digestive system function.
- Delivers a robust probiotic component to help restore beneficial gut flora, influencing mood, metabolism, and overall well-being.
- Targets the gut-brain axis with multiple bioactive compounds that may support healthy inflammatory responses and microbial balance.
- Regulatory Status
Gut Peptide Complex is not approved by the U.S. Food and Drug Administration (FDA) for any specific medical indication. If you need FDA-approved therapy, please consult a qualified healthcare professional about alternative options. - Potential Uses & Research
Inflammation Reduction & Tissue Support- Ingredients like KPV and BPC have been examined (largely in animal models) for their potential to reduce inflammation and aid in healing soft tissues (e.g., tendons, ligaments).
- GHK-Cu has shown promise in supporting regeneration through angiogenesis (new blood vessel formation) and antioxidant activity.
- Ingredients like KPV and BPC have been examined (largely in animal models) for their potential to reduce inflammation and aid in healing soft tissues (e.g., tendons, ligaments).
- Gut-Brain Axis & Microbiota Balance
- The 11-strain, 25-billion-CFU probiotic blend may help foster a healthier microbiome, influencing digestion, nutrient absorption, and possibly mental health outcomes.
- Emerging research suggests a balanced gut microbiota can positively affect mood, immune responses, and metabolic function.
- The 11-strain, 25-billion-CFU probiotic blend may help foster a healthier microbiome, influencing digestion, nutrient absorption, and possibly mental health outcomes.
- Metabolic & Anti-Aging Considerations
- Healthy gut flora is associated with better weight management and metabolic health.
- Probiotics and certain peptides (e.g., GHK-Cu) may contribute to healthy aging by supporting tissue repair and reducing oxidative stress.
- Healthy gut flora is associated with better weight management and metabolic health.
- Limited Human Trials
- Though promising in animal and in vitro research, large-scale, well-controlled human studies are limited for several components in Gut Peptide Complex. More robust research is needed to confirm long-term safety, efficacy, and standardized dosing.
- Though promising in animal and in vitro research, large-scale, well-controlled human studies are limited for several components in Gut Peptide Complex. More robust research is needed to confirm long-term safety, efficacy, and standardized dosing.
- Contraindications & Precautions
You should not use Gut Peptide Complex if you:- Are pregnant, planning to become pregnant, or breastfeeding, unless specifically advised by a qualified medical professional.
- Have known allergies or sensitivities to any of its ingredients, including probiotics or peptide formulations.
- Have severe or unstable medical conditions (e.g., uncontrolled diabetes, advanced kidney/liver disease) without first consulting a healthcare provider.
- Are pregnant, planning to become pregnant, or breastfeeding, unless specifically advised by a qualified medical professional.
- Please consult your healthcare provider before using Gut Peptide Complex if you have:
- A history of autoimmune or chronic inflammatory conditions.
- Active malignancies or are undergoing cancer treatments.
- Any other significant medical conditions requiring ongoing care and monitoring.
- A history of autoimmune or chronic inflammatory conditions.
- Possible Side Effects
While formal large-scale human safety data are limited, anecdotal reports and smaller studies suggest the following potential side effects:- Gastrointestinal Upset
- Mild cramping, changes in bowel habits, or bloating may occur as part of probiotic introduction.
- Consult a healthcare professional if symptoms are severe or persistent.
- Mild cramping, changes in bowel habits, or bloating may occur as part of probiotic introduction.
- Allergic Reactions
- May include rash, itching, swelling of the face/lips/tongue, or difficulty breathing.
- Stop use immediately and seek medical attention for any severe allergic symptoms.
- May include rash, itching, swelling of the face/lips/tongue, or difficulty breathing.
- Changes in Mood or Energy
- Modulating the gut-brain axis may affect neurotransmitters and, therefore, mood, energy levels, or sleep patterns.
- Modulating the gut-brain axis may affect neurotransmitters and, therefore, mood, energy levels, or sleep patterns.
- Other Potential Side Effects
- Because large-scale human research is limited, other side effects may remain unidentified. Always report unusual symptoms to a healthcare provider.
- Because large-scale human research is limited, other side effects may remain unidentified. Always report unusual symptoms to a healthcare provider.
- Gastrointestinal Upset
- Administration & Dosage
- Route & Formulation
- Gut Peptide Complex is typically supplied in oral capsule form.
- Gut Peptide Complex is typically supplied in oral capsule form.
- Dosage
- There is no standard dosing protocol. A qualified practitioner may suggest a dosage based on individual factors such as health status, goals, and tolerance.
- There is no standard dosing protocol. A qualified practitioner may suggest a dosage based on individual factors such as health status, goals, and tolerance.
- Monitoring
- Your healthcare provider may recommend follow-up appointments to track your response and address potential side effects.
- Report any new or worsening symptoms to your provider.
- Your healthcare provider may recommend follow-up appointments to track your response and address potential side effects.
- Route & Formulation
- Warnings & Limitations
- Off-Label and Experimental Use
- Gut Peptide Complex is not FDA-approved for any specific indication. Its use should be considered experimental or off-label.
- Gut Peptide Complex is not FDA-approved for any specific indication. Its use should be considered experimental or off-label.
- Limited Human Data
- Much of the supportive data is derived from animal or in vitro studies; caution is advised until more robust clinical data are available.
- Much of the supportive data is derived from animal or in vitro studies; caution is advised until more robust clinical data are available.
- Not a Substitute for Standard Medical Care
- Gut Peptide Complex should not replace treatments prescribed for inflammatory, metabolic, or gastrointestinal disorders.
- Gut Peptide Complex should not replace treatments prescribed for inflammatory, metabolic, or gastrointestinal disorders.
- Risk vs. Benefit
- Discuss the potential advantages and risks with a qualified healthcare professional before initiating use.
- Discuss the potential advantages and risks with a qualified healthcare professional before initiating use.
- Off-Label and Experimental Use
- Drug Interactions
- Concomitant Medications
- Inform your healthcare provider about any prescription or over-the-counter medications, supplements, and herbal products you take.
- Inform your healthcare provider about any prescription or over-the-counter medications, supplements, and herbal products you take.
- Unknown Interactions
- While no major interactions have been firmly established, the effects of combined usage (particularly on inflammation, immune function, and gut flora) remain incompletely characterized.
- While no major interactions have been firmly established, the effects of combined usage (particularly on inflammation, immune function, and gut flora) remain incompletely characterized.
- Concomitant Medications
- Storage & Handling
- Temperature & Light
- Store in a cool, dry place. Some formulations may require refrigeration—follow specific guidelines provided by your pharmacist or compounder.
- Store in a cool, dry place. Some formulations may require refrigeration—follow specific guidelines provided by your pharmacist or compounder.
- Expiration
- Do not use Gut Peptide Complex beyond its expiration date or if signs of contamination or degradation are present.
- Do not use Gut Peptide Complex beyond its expiration date or if signs of contamination or degradation are present.
- Temperature & Light
- Reporting Adverse Events
- Seek Immediate Medical Attention
- Call 911 or go to the nearest emergency room if you experience severe reactions like trouble breathing, significant swelling, or confusion.
- Call 911 or go to the nearest emergency room if you experience severe reactions like trouble breathing, significant swelling, or confusion.
- Adverse Event Reporting
- Contact your healthcare provider to report any unexpected side effects.
- You can also file a report with the FDA’s MedWatch Program at 1-800-FDA-1088 or online at www.fda.gov/medwatch.
- Contact your healthcare provider to report any unexpected side effects.
- Seek Immediate Medical Attention
- Disclaimer
- Not Evaluated by the FDA
- Gut Peptide Complex has not been approved by the FDA to diagnose, treat, cure, or prevent any disease.
- Gut Peptide Complex has not been approved by the FDA to diagnose, treat, cure, or prevent any disease.
- Educational Purposes Only
- This information is general education and is not intended to replace professional medical advice.
- This information is general education and is not intended to replace professional medical advice.
- Individual Variation
- Responses vary among individuals; no outcomes are guaranteed.
- Responses vary among individuals; no outcomes are guaranteed.
Questions or Concerns?
If you have further questions about Gut Peptide Complex—its components, impact on the gut-brain axis, or suggested uses—please seek advice from a qualified healthcare professional.
Methylene Blue: Important Safety Information
1. Introduction
What is Methylene Blue?
Methylene Blue (MB), also known as methylthioninium chloride, is a synthetic compound historically used as a diagnostic dye and therapeutic agent. In supplement form, it is being explored for its potential antioxidant, neuroprotective, and mitochondrial-supportive properties.
Mechanism of Action
Methylene Blue supports cellular health primarily by enhancing mitochondrial function, acting as an alternative electron carrier to bypass impaired complexes in the electron transport chain. It may help reduce oxidative stress and support ATP (energy) production, especially in the brain and other high-demand tissues.
Regulatory Status
Methylene Blue is not FDA-approved as a dietary supplement for any disease or medical condition. Its use in supplement form should be considered experimental and investigational. It is available over-the-counter in low doses, often marketed for cognitive support and cellular energy.
2. Potential Uses & Research
Mitochondrial Support
MB may improve mitochondrial efficiency and reduce reactive oxygen species (ROS), making it a candidate for anti-aging support, cellular repair, and general vitality.
Cognitive Function
Studies suggest MB may enhance memory, focus, and mood, and is being investigated for use in Alzheimer’s disease and other neurodegenerative conditions by reducing beta-amyloid plaques and oxidative stress in the brain.
Longevity & Skin Health
Preliminary data indicate that MB may attenuate cellular aging markers, promote collagen synthesis, and support youthful skin appearance through fibroblast rejuvenation.
Note: These benefits are theoretical and based primarily on preclinical and early-stage human studies. Human evidence remains limited.
3. Contraindications & Precautions
You should not use Methylene Blue supplements if you:
- Have a known G6PD deficiency (can cause hemolytic anemia).
- Are pregnant or breastfeeding.
- Are currently taking SSRIs, SNRIs, MAOIs, or other serotonergic medications (risk of serotonin syndrome).
- Have a history of allergy or hypersensitivity to methylene blue.
Consult your healthcare provider before use if you have:
- Liver or kidney disease
- Neurological or psychiatric disorders
- Any condition requiring ongoing medical treatment
4. Possible Side Effects
Although low-dose oral Methylene Blue is generally well tolerated, possible side effects may include:
Mild and Common
- Urine or stool discoloration (blue or greenish tint)
- Digestive upset (nausea, abdominal discomfort)
- Headache or dizziness
Less Common but Serious
- Mood changes or mild agitation
- Photosensitivity
- Allergic reaction (rash, itching—discontinue use if these occur)
Risk of Serotonin Syndrome
When combined with serotonergic drugs, MB may raise serotonin levels excessively. Avoid concurrent use unless under medical supervision.
Always begin with the lowest effective dose and monitor your response. Discontinue use and consult a healthcare professional if adverse symptoms occur.
5. Administration & Dosage
Formulation
This product contains Methylene Blue in capsule form for oral use only.
Suggested Use
- Follow the serving size recommended on the label or as directed by a qualified healthcare professional.
- Do not exceed suggested dosage.
- Take with food or water to minimize GI discomfort.
Tolerance & Monitoring
- Begin with a low dose to assess tolerance.
- Some users may experience dose-dependent effects; individualized adjustment may be appropriate under guidance.
6. Warnings & Limitations
- For dietary supplement use only; not intended to diagnose, treat, cure, or prevent any disease.
- Should not be used as a substitute for medical treatment.
- Avoid use in children unless recommended by a healthcare professional.
- Do not combine with serotonergic agents, especially without supervision.
7. Storage & Handling
- Store in a cool, dry place, away from sunlight and heat.
- Keep out of reach of children.
- Do not use if the seal is broken or the product shows signs of contamination.
8. Disclaimer
- These statements have not been evaluated by the FDA.
- Individual responses may vary.
- Consult a licensed healthcare provider before starting any new supplement, especially if you are taking medications or managing chronic health conditions.
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Prescription products require an online evaluation by a licensed medical professional. Medications are prescribed by licensed physicians as part of our programs, and actual product packaging may vary. The FDA does not review compounded medications for safety or effectiveness. For prescription items, IVY RX will arrange a consultation with a qualified healthcare provider. If approved, prescriptions can be filled at a partner pharmacy.
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