
Using anti-nausea medication like Ondansetron (Zofran®) alongside GLP-1 medications is a common strategy to assist in smooth dosage increases by managing potential side effects like nausea.
Reduces nausea
Improves medication adherence
Enables smoother dosage increases

Take ondansetron by mouth with water; it may be taken with or without food.
Common:
- Headache
- Constipation
- Dizziness
Rare But Serious:
- Irregular heartbeat
- Severe dizziness/fainting
- Allergic reaction (swelling, rash, trouble breathing)
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No, Ivy Rx does not require insurance. We keep things simple with transparent pricing, straightforward billing, and affordable generic options—making it easier than ever to take care of yourself.
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Ondansetron is an FDA-approved prescription medication used to prevent and treat nausea and vomiting. It may be prescribed for off-label uses at a provider’s discretion.
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
As with other medications, ondansetron can interact with alcohol and certain prescription and non-prescription medications and herbal products.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions, and additional information.
To report suspected adverse reactions to ondansetron, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
Note: The above statements have not been evaluated by the Food and Drug Administration for off-label use. This product is not intended to diagnose, treat, cure, or prevent any disease.
Tell your healthcare provider about your medical history prior to taking ondansetron, especially if you have:
Use caution when consuming alcohol, as it may worsen side effects such as dizziness or drowsiness.
Never share ondansetron with other people.
Stop using ondansetron and get medical help right away if you are experiencing heart rhythm abnormalities or symptoms of a serious allergic reaction including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; or fainting.
If you experience a medical emergency, call 911 or go to the nearest emergency room.