15 Celebrities Who Took Ozempic for Weight Loss (& Results!)

Talk of celebrities using Ozempic for weight loss have flooded social media, but which have actually confirmed it?

This article profiles 15 famous people who have spoken publicly about their experience with Ozempic, from Oprah's maintenance approach to Sharon Osbourne's cautionary tale. 

You'll see their Ozempic results, learn what these celebs on Ozempic said about side effects, and discover how GLP-1 treatments work.

No rumors. Just confirmed cases with direct quotes and real results.

What Is Ozempic and Why Are Celebrities Turning to It?

Ozempic is a GLP-1 receptor agonist containing semaglutide, a medication that mimics hormones regulating appetite and blood sugar. 

It slows stomach emptying and signals fullness to your brain, and reduces food cravings.

Most Celebrities using Ozempic often mention similar drugs:

• Ozempic/Wegovy (semaglutide; both contain the same active ingredient)
• Mounjaro (tirzepatide, a dual GIP/GLP-1 agonist)

These medications require weekly injections and medical supervision. 

You can learn more about the differences between GLP-1 and Ozempic, or explore other personalized GLP-1 and Ozempic treatment options.

Celebrities Who Have Confirmed Using Ozempic

These Ozempic celebrities personally confirmed their use in interviews or through verified statements, not tabloid speculation. Here's what they said about results, side effects, and whether it worked.

1. Sheryl Underwood — Lost 100 lb with Wegovy

Drug: Wegovy (semaglutide)

Before treatment:

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After treatment:

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TV host Sheryl Underwood told People she lost 95-100 lbs by pairing Wegovy with diet and exercise. 

She joked that she's "almost a baby Kardashian" and emphasised that injections are just part of her regimen.

Results: Roughly 100 lb lost with Wegovy and lifestyle changes.

2. Elon Musk — Credits Wegovy for Trim Physique (And fasting)

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Drug: Wegovy (semaglutide)

Elon responded on X (Twitter) that his slimmer look came from fasting and Wegovy.

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Results: Significant weight loss; exact figure not stated.

3. Serena Williams — Lost 31 lb with GLP-1

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Drug: GLP-1 medication (not named)

Tennis legend Serena Williams told Today.com in 2025 that she struggled to reach her goal weight despite intense training. She lost over 31 lb using a GLP-1, adding the medication "enhanced everything I was already doing."

Results: 31 lb lost while continuing vigorous exercise.

4. Jim Gaffigan — 50 lb Loss on Mounjaro

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Drug: Mounjaro (tirzepatide)

Comedian Jim Gaffigan told The View that “I have gotten skinny. And it’s none of my own willpower. It’s a shot in the stomach. That works wonders. I don’t know why people are afraid to admit it. It seems strange.”

He lost around 50 lb after starting Mounjaro. He described the injections as a "shot in the stomach that works wonders" and said he's grateful for his new life.

Results: About 50 lb lost with Mounjaro.

5. Amy Schumer — Switched from Ozempic to Mounjaro

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Comedian Amy Schumer told Andy Cohen on Watch What Happens Live in June 2023 that she tried Ozempic but felt extremely sick and couldn't play with her son. 

"I was so skinny, and he's throwing a ball at me and [I couldn't]," she said. She later switched to Mounjaro and told fans on Instagram she's having "an excellent experience." Schumer urged celebrities to stop lying about weight-loss drugs: "Everyone has been lying, saying, 'Oh, smaller portions.' Like shut the f— up."

Results: Lost 30 pounds on Ozempic but stopped due to severe nausea; successfully using an alternative GLP-1 treatment: Mounjaro (tirzepatide).

6. Kathy Bates — Lost an Additional 20 lb on Ozempic

Drug: Ozempic (semaglutide)

Actress Kathy Bates told People’s Magazine she lost about 20 lb on Ozempic after losing 80 lb through diet and exercise. She emphasized that the drug is not a quick fix and still requires portion control.

Results: Added ~20 lb loss on top of lifestyle changes.

7. Tracy Morgan — Weekly Ozempic for Appetite Control

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Drug: Ozempic (semaglutide)

Actor Tracy Morgan told Today he takes an Ozempic shot every Thursday, calling it "my appetite suppressant." He noted the drug cuts his appetite "in half."

Results: No specific weight numbers, but acknowledged appetite reduction.

8. Lauren Manzo — 50 lb on Mounjaro

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Drug: Mounjaro (tirzepatide)

Reality TV star Lauren Manzo told People’s magazine that Mounjaro "saved my life" by reducing food noise and helping her address weight anxiety. She lost another 50 lb on the injections.

Results: Around 50 lb lost on Mounjaro.

9. Renée Graziano — with Mounjaro

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Drug: Mounjaro (tirzepatide)

Renée Graziano confirmed on Instagram that she used weekly Mounjaro shots during the first five months of her weight-loss plan. In her May 2025 post, she wrote that she was “down 52 lb,” and shared that the change made her feel younger, clearer, and more confident. She also noted that therapy, supplements, and work on her insecurity were part of her progress.

Results: Lost about 52 lb on Mounjaro.

10. Fat Joe — Maintains 200+ lb Weight Loss

Fat Joe Before:

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Fat Joe was near his heaviest at the 1999 Grammys/ Getty.

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Drug: Ozempic or Wegovy (semaglutide)

Rapper Fat Joe told Men’s Health that Ozempic limits him to "only two pieces of [his] favourite stuff," helping him maintain the 200+ lb he previously lost. He still follows a low-carb diet and continues to exercise.

Results: Maintains massive weight loss and avoids regaining weight.

11. Chrissy Teigen — Used Ozempic After Loss of Son

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Drug: Ozempic (semaglutide)

Chrissy Teigen posted on Instagram that she began taking Ozempic after the loss of her son Jack, saying she felt trapped in a body that didn't feel like her own.

Results: Shared weight loss but no specific numbers.

12. Remi Bader — Regained Weight After Stopping

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Drug: Ozempic (semaglutide)

Model Remi Bader said she was prescribed Ozempic for PCOS and pre-diabetes, but stopped due to side effects. 

She later gained back more weight than she lost, telling Page Six the rebound "made me anti" the drug.

Results: Short-term weight loss followed by weight regain. Long-term regain is normal with every weight loss intervention, including weight loss without a GLP-1, unless lifestyle changes are made. 

13. Emily Simpson — Short-Term Ozempic Use

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Drug: Ozempic (semaglutide)

Real Housewives of Orange County star Emily Simpson said she used Ozempic briefly to "jump-start" her weight loss, but stopped after losing 5-10 lbs, and she also faced criticism for it. But didn’t stop until she felt nauseous and lethargic, so she focused on exercise and strength training instead.

Results: 5-10 lbs lost before discontinuing due to side effects

14. Caroline Stanbury — Used Ozempic After IVF

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Drug: Ozempic (semaglutide)

Real Housewives of Dubai star Caroline Stanbury told People she gained 18 lb after an IVF cycle and used Ozempic to return to her normal weight. She praised it as "an incredible tool" but said drinking alcohol while on it led to projectile vomiting.

Results: Returned to pre-IVF weight; experienced severe nausea with alcohol. It is recommended to reduce alcohol consumption on a GLP-1.

15. Heather Gay — Modest Results on Ozempic

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Drug: Ozempic (semaglutide)

Real Housewives of Salt Lake City star Heather Gay said she had been taking Ozempic but only lost "a few pounds." She also noted that being on the drug prompted people to treat her differently.

Results: Only a small amount of weight loss

Compare different weight loss injection options to find what works for you.

Why Celebrities Are Turning to Ozempic

Celebrities using Ozempic benefit from medically supervised weight management with proven results. GLP-1 prescriptions in the U.S. surged in recent years, driven by clinical evidence, reduced stigma, and the physical results people see.

Medical support for weight loss has shifted from shame to acceptance. Celebrities now openly discuss GLP-1 treatments, normalizing prescription medications as tools — not shortcuts.

Ready to explore GLP-1 treatment? Start your personalized consultation with IvyRx today and get affordable access to semaglutide with medical supervision.

You can also explore other alternatives to Ozempic if you want more options.

Common Misconceptions About Ozempic

• "Ozempic is a miracle drug that works instantly" — False. Weight loss takes 8-12 weeks and requires diet changes and exercise.
• "You can stop anytime without consequences" — False. Many people regain weight after stopping, as Remi Bader experienced
• "Anyone can use Ozempic" — False. It requires medical clearance, contraindication screening, and dose titration.
• "Side effects are rare" — False. Nausea, vomiting, and GI issues affect 30-50% of users initially.

Pro Tip: Ozempic works by changing how semaglutide interacts with your body — it's not magic; it's biology. Medical supervision ensures safe dose adjustments and manages side effects.

Wondering about compounded semaglutide vs Ozempic or pills vs injections? Both options work, but dosing differs.

Not Just for Celebrities: Get Affordable GLP-1 Treatments with IvyRx

You don't need celebrity status to access GLP-1 treatment. 

IvyRx offers personalised GLP-1 injections starting at $175 per month, as well as an option for GLP microdosing treatment. 

With this treatment, you can begin your weight loss journey even though you’re not a celebrity.

Our licensed providers prescribe compounded GLP-1, providing medical consultations, dose optimisation, and ongoing support, no insurance needed.

Start your weight loss journey today. 

Get your personalized GLP-1 treatment plan with IvyRx now.

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