6 Best NAD Nasal Sprays for Longevity & Metabolic Health [in 2025]

Looking for the best NAD nasal spray but overwhelmed by the options?

With new products popping up each year, it’s hard to know which ones are safe, effective, and actually worth the price. The good news? We’ve done the work for you.

Below, we break down the 6 best NAD+ nasal sprays for 2025, covering key details like pricing strengths, weaknesses, and real use cases. 

Let’s start with a quick comparison of our top picks.

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Prices are estimated starting costs as of 2025. Exact pricing may vary by retailer.

1. IVY RX: Best NAD Nasal Spray for Daily Energy and Longevity

If you're looking for a fast, needle-free way to raise your NAD+ levels, IVY RX's nasal spray delivers. Each dose contains 300 mg/mL of pharmaceutical-grade NAD+. This is delivered through a fine mist that absorbs quickly through your nasal lining. No pills. No injections. 

Key Benefits

You’ll get three big benefits from IVY’s spray: more energy, sharper focus, and strong anti-aging support.

Quick energy boost

IVY's nasal delivery ensures that NAD+ reaches your system quickly. If you're feeling drained or slow, it gives you a fast pick-me-up to stay sharp and energized all day.

Sharper thinking

It fuels your brain cells to keep you focused and clear-headed. Whether you're working hard, studying, or avoiding that mid-afternoon slump, it helps maintain mental clarity.

Better aging defense

The formula supports key enzymes that help repair DNA and slow down age-related cellular decline. It’s a powerful way to help your body fight the effects of aging at the cellular level.

Pricing

The cost of IVY’s NAD+ nasal spray is the same price at every dose: $179 per month.

Where IVY shines

• Fast and needle-free: You do not need a clinic visit or injection. Just spray and go. It saves time and removes the stress of needles.
• Consistent daily dosing: Each spray delivers a fixed amount of NAD+. This makes it easy to track your intake and stay consistent.
• Clinically backed formula: IVY uses pharmaceutical-grade NAD+ with oversight from U.S. board-certified providers. You get both quality and confidence.

Verified Customer reviews

Review #1

• Trustpilot

Review #2

• Trustpilot

Who IVY is best for

• Busy professionals and biohackers: If you want to stay sharp without relying on caffeine or infusions, IVY is your go-to for daily cognitive support.
• Needle-averse users: Prefer a non-invasive, at-home option? IVY delivers fast NAD+ without needles, giving you a simple and effective solution.

Access NAD+ Nasal spray from Ivy today

2. Empower Pharmacy NAD+ Nasal Spray

Empower Pharmacy offers a prescription-based, custom-compounded NAD+ nasal spray formulated in FDA-registered facilities. It’s created for patients with specific dosing needs. You can use it for mitochondrial function, neuroprotection. It also works as a supportive therapy in addiction recovery. 

Unlike over-the-counter sprays, Empower’s formula requires a valid prescription and medical oversight. That said, you get higher potency and clinical-grade precision.

Key features

• Prescription-strength dosing: The spray is compounded per patient needs. This allows for higher or more precise NAD+ concentrations.
• Pharmacy-grade manufacturing: Produced under USP standards in 503A and 503B facilities that meet FDA registration requirements.
• Quick nasal absorption: Designed to enter the bloodstream rapidly through the nasal mucosa, offering fast mitochondrial and neuroprotective effects.
• Medical oversight required: Use is monitored by licensed prescribers and pharmacists. This ensures safety and effectiveness.

Pricing

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Where Empower Pharmacy NAD+ Nasal Spray shines

• Custom dosing for serious use: You get full control over your dosage, ideal if you're using NAD+ therapeutically or long term.
• Produced with strict quality standards: All sprays are made in FDA-registered labs with pharmacist supervision.

Where Empower Pharmacy NAD+ Nasal Spray falls short

• Prescription required: You’ll need to go through a prescriber and complete medical intake to access it.
• Regulatory scrutiny: Empower Pharmacy has faced FDA warnings in unrelated areas, which may raise concerns for some users.
• Opaque pricing and availability: No public MSRP, and product access depends on provider discretion and location.

Customer reviews

•  No verifiable customer reviews available. 

Who Empower Pharmacy NAD+ Nasal Spray is best for

• Medically supervised patients: Best suited for individuals who require high-potency NAD+ and are working with a licensed healthcare provider.

3. Drip Hydration NAD+ Nasal Spray

Drip Hydration’s NAD+ Nasal Spray offers a high-potency, at-home solution for boosting energy and supporting longevity. The 300 mg/mL spray comes with a subscription option and includes virtual consultations with licensed professionals. 

This spray is designed for those seeking a convenient and effective way to increase NAD+ levels without the need for injections or clinic visits.

Key features

• High potency: Each 15 mL bottle contains a 300 mg/mL concentration, offering approximately 150 sprays (30 mg per spray).
• Convenient delivery: No needles or clinic visits required. Just a simple nasal spray for fast absorption.
• Subscription model: Get monthly delivery, including virtual consultations, for ongoing support and easy access.
• No fillers: Only NAD+ is included in the formula, with no added ingredients or fillers.

Pricing

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Where Drip Hydration NAD+ Nasal Spray shines

• Convenience: With home delivery and virtual consultations, Drip Hydration makes it easy to integrate NAD+ support into your daily routine.
• Professional oversight: The virtual consultation ensures safe and personalized use, with licensed professionals guiding your dosage and usage.
• Purity: The formula is free from fillers, delivering just pure NAD+ to maximize potency.

Where Drip Hydration NAD+ Nasal Spray falls short

• Cost: The subscription and one-time purchase price may be higher compared to some over-the-counter alternatives.
• Limited clinical data: While the product is promising, there’s a lack of detailed clinical research backing its long-term effectiveness.

Customer reviews

•  No verifiable customer reviews available. 

Who Drip Hydration NAD+ Nasal Spray is best for

• Professionally guided users: Ideal for those looking to boost energy, focus, and anti-aging benefits with a high-quality product, along with the added convenience of virtual consultations and professional oversight.

4. Lovely Meds NAD+ Nasal Spray

Lovely Meds offers a 15mL nasal spray formulated to help improve cognitive function, reduce fatigue, and support anti-aging efforts. Priced at $199, the product promises quick shipping and discreet packaging. 

This spray is ideal for individuals seeking an easy and effective way to boost mental clarity, increase energy, and promote overall well-being without the need for complex routines.

Key features

• Mental clarity support: Aims to reduce brain fog and improve focus, helping you stay sharp throughout the day.
• Energy boost: Designed to fight fatigue and give you a quick energy lift, helping you power through busy moments.
• Anti-aging benefits: Targets oxidative stress, supporting cellular health to promote a more youthful feel.
• Fast delivery: Ships within 24–48 hours with plain, unmarked packaging, ensuring privacy and convenience.

Pricing

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Where Lovely Meds NAD+ Nasal Spray shines

• Convenient administration: Nasal spray form allows for easy and quick use.
• Rapid delivery: Orders are processed and shipped within 24–48 hours.
• Discreet packaging: Ensures privacy with plain, unmarked packaging.

Where Lovely Meds NAD+ Nasal Spray falls short

• Limited dosage information: Lacks detailed instructions on frequency and quantity of use.
• No clinical trials: Absence of published studies to validate efficacy claims.
• Unclear ingredient sourcing: Does not specify the origin or quality of NAD+ used.

Customer reviews

Review #1

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• Trustpilot

Review #2

• Trustpilot

Who Lovely Meds NAD+ Nasal Spray is best for

• High-performing individuals: People seeking a convenient and quick method to enhance mental clarity and reduce fatigue will find the product a great fit. 

5. MintRx NAD+ Nasal Spray

MintRx offers a 15mL nasal spray designed to boost energy, improve cognitive function, and support anti-aging. Priced at $179 for a one-time purchase, it provides an easy, needle-free alternative to traditional NAD+ treatments. 

This spray is perfect for those looking for a convenient way to enhance mental clarity, fight fatigue, and support overall well-being without the need for injections.

Key features

• Enhanced energy levels: Helps reduce fatigue and increase stamina by boosting cellular energy production.
• Cognitive support: Improves focus, memory, and mental clarity for better daily performance.
• Anti-aging & cellular repair: Supports DNA repair and reduces oxidative stress, promoting a more youthful feeling.
• Needle-free convenience: The nasal spray offers a quick and easy application, eliminating the need for injections.

Pricing

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Where MintRx NAD+ Nasal Spray shines

• Convenient administration: Nasal spray form makes it fast and straightforward to use.
• Rapid delivery: Ships within 24–48 hours, with plain, unmarked packaging for privacy.
• Affordable alternative: Offers the benefits of injectable NAD+ at a relatively lower cost.

Where MintRx NAD+ Nasal Spray falls short

• Potential tolerability issues: Users may experience nasal irritation, burning, a runny nose, headaches, or mild nausea, which can deter consistent use.
• Limited clinical evidence: Lack of independent trials on the nasal formulation; most data is based on injectable NAD+ studies.
• Late deliveries: Many users have mentioned not receiving their nasal spray orders at the due delivery date. 

Customer reviews

Review #1

• Trustpilot

Who MintRx NAD+ Nasal Spray is best for

• Individuals seeking a quick energy boost: The spray is designed to boost energy, enhance mental clarity, and support cellular health for improved focus, recovery, and longevity.

6. LiveWellRX NAD+ Nasal Spray  

LiveWellRX offers a 15mL bottle of high-concentration NAD+ nasal spray, with 300mg of NAD+ per milliliter, priced at $215. It’s designed to provide users with improved energy, cognitive function, and overall well-being. 

The rapid nasal absorption is a convenient, needle-free alternative for those looking to boost their cellular health. It provides an easy-to-use alternative to more invasive NAD+ treatments.

Key features

• High-concentration formula: Each spray delivers a potent 300mg dose of NAD+, providing significant support for energy production and cellular repair.
• Premium-quality NAD+ Nasal: Pharmaceutical-grade and sourced from trusted suppliers, ensuring both safety and effectiveness.
• Convenient telehealth consultations: LiveWellRX offers easy online consultations with healthcare professionals for personalized NAD+ nasal spray prescriptions.  
• Fast, discreet shipping: Quick and private delivery of the NAD+ Nasal spray allows users to start benefiting from the product as soon as possible.

Pricing

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Where LiveWellRX NAD+ Nasal Spray shines

• Faster energy boost: The high concentration of NAD+ in LivewellRX NAD+ nasal spray translates to quicker results, helping to increase energy production more rapidly.
• Telehealth accessibility: LiveWellRX offers online consultations with healthcare providers, ensuring that you get personalized recommendations for your needs.

Where LiveWellRX NAD+ Nasal Spray falls short

• High price point: At $215 for 15mL, it’s on the expensive side compared to other NAD+ products.
• Limited dosage instructions: The product lacks detailed guidance on how often to use it or how much to apply, leaving room for uncertainty.
• No clinical trials: There is no peer-reviewed research available to validate the effectiveness or safety of this specific nasal formulation.

Customer reviews

• No verifiable customer reviews. 

Who LiveWellRX NAD+ Nasal Spray is best for

• Ideal for those seeking higher concentration: Individuals looking for a higher concentration of NAD+ for faster, more effective energy boosts and enhanced overall well-being.

How to Choose an NAD Nasal Spray?

Choosing the right NAD nasal spray depends on potency, formulation quality, absorption efficiency, and professional support. These ensure you get safe, effective, and personalized results.

Potency Per Spray

Always check how much NAD+ is delivered with each spray. Higher-dose formulas may deliver fast results but often come with increased cost or a higher risk of side effects. 

IvyRX uses a clinician-reviewed concentration designed for daily use. This gives you a safe balance between effectiveness and tolerability. 

Formulation and Bioavailability

Not all sprays absorb equally. Look for advanced delivery formats like liposomal or buffered solutions, which can improve how much NAD+ actually reaches your bloodstream. 

IvyRX is formulated for high mucosal uptake without stinging. It offers smooth absorption and dependable performance over time.

Safety Oversight and Guidance

If you're using NAD+ regularly, it’s worth having a licensed provider involved. Medical supervision helps ensure your dose is appropriate and monitored. 

IvyRX includes a professional consultation and built-in provider support, so you’re never left guessing about your plan or progress.

Ease of Use and Routine Fit

The best NAD+ spray is one you’ll use consistently and will help you increase NAD+ faster than doing it naturally. Look for portable bottles, simple dosing instructions, and non-invasive formats. IVY RX checks all these boxes with its travel-ready bottle and once-daily spray routine. You can easily build it into your day.  

Cost-Efficiency

Low-cost sprays often come with low potency. That means you may need more sprays to feel results. IvyRX offers a subscription model that includes strong dosing and medical support. You get value beyond just the price tag. 

Want help making the right call? Explore IVY RX’s full guide to NAD+ nasal sprays.

Boost Longevity, Metabolic Health, and Energy With IVY RX NAD+ Nasal Spray

Looking for a high-purity NAD+ solution that actually fits your routine? IVY RX NAD+ Nasal Spray delivers 300 mg/mL of pharmaceutical-grade NAD+ with fast nasal absorption, once-daily dosing, and licensed provider support. It’s built for people who want real results, without injections or guesswork.

Whether you're optimizing for longevity, clarity, or recovery, IVY RX offers a smarter approach to NAD+.

Explore IVYs NAD+ Nasal spray or learn more about what NAD+ Nasal Spray is

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